منابع مشابه
The planar polarity pathway
to the brain and receive high-order commands and inputs from it. That is, much of the planning, computation and execution of stereotypic arm movements are conducted within the arm neural system itself. Accordingly, natural-looking arm extension movements can be generated in amputated arms. This organization may be an optimal solution for the motor control of highly redundant flexible appendages...
متن کاملPlanar Cell Polarity Signaling Pathway in Congenital Heart Diseases
Congenital heart disease (CHD) is a common cardiac disorder in humans. Despite many advances in the understanding of CHD and the identification of many associated genes, the fundamental etiology for the majority of cases remains unclear. The planar cell polarity (PCP) signaling pathway, responsible for tissue polarity in Drosophila and gastrulation movements and cardiogenesis in vertebrates, ha...
متن کاملThe Wnt5/planar cell polarity pathway regulates axonal development of the Drosophila mushroom body neuron.
Axonal development is a fundamental process for circuit formation in the nervous system and is dependent on many cellular events, including axon initiation, elongation, guidance, and branching. The molecular mechanisms underlying these events have been well studied, especially for axon guidance. In the presence of a guidance cue, the polarization of a growth cone precedes the turning response, ...
متن کامل03-P047 The planar polarity pathway and trachea formation in the Drosophila embryo
Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces Pablo Oteiza, Mathias Koeppen, Michael Krieg, Stephan Preibisch, Steffen Haertel, Daniel Mueller, Carl-Philipp Heisenberg, Miguel Concha 1 University of Chile, Santiago, Chile 2 Max Planck Institute for Molecular Cell Biology and Genetics, Dresd...
متن کاملShaping the mammalian auditory sensory organ by the planar cell polarity pathway.
The human ear is capable of processing sound with a remarkable resolution over a wide range of intensity and frequency. This ability depends largely on the extraordinary feats of the hearing organ, the organ of Corti and its sensory hair cells. The organ of Corti consists of precisely patterned rows of sensory hair cells and supporting cells along the length of the snail-shaped cochlear duct. O...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2008
ISSN: 0960-9822
DOI: 10.1016/j.cub.2008.07.055